Blobel, Sabatini and Dobberstein proposed that the site of protein synthesis is determined by information contained in the N-terminal portion of the protein, the first part to emerge from the ribosome. What did they call their proposal?
A)the Chemiosmotic Hypothesis
B)the Posttranslational Hypothesis
C)the SRP Hypothesis
D)the Signal Hypothesis
E)the Co-translational Hypothesis

Question

Quizplus · Accepted Answer

Blobel, Sabatini and Dobberstein called their proposal the Signal Hypothesis, which suggests that the site of protein synthesis is determined by information contained in the N-terminal portion of the protein that serves as a signal for targeting the protein to the correct cellular location.

Blobel, Sabatini and Dobberstein Proposed That the Site of Protein