What happens to COPI-coated vesicles within the cell when the cell is treated with GTP analogues that can not be hydrolyzed?
A)They accumulate in the nucleus.
B)They accumulate in the cytoplasm.
C)They fuse into one giant vesicle in the cytoplasm.
D)They decrease substantially in number in the nucleus.
E)They decreasd substantially in number in the cytoplasm.

Question

Quizplus · Accepted Answer

COPI-coated vesicles transport proteins between the Golgi and ER. When GTP analogues that cannot be hydrolyzed are used, the COPI-coated vesicles cannot release their coat and therefore cannot fuse with their target membrane. This results in the accumulation of COPI-coated vesicles in the cytoplasm.

What Happens to COPI-Coated Vesicles Within the Cell When the Cell