What is responsible for recognizing lysosomal enzymes and localizing them to the lysosomes? (Select all correct choices)
A)mannose 6-phosphate receptors
B)MPRs
C)integral membrane proteins that span the TGN membranes
D)intraGolgi receptors that reside in the TGN lumen

Question

Quizplus · Accepted Answer

Mannose 6-phosphate receptors (MPRs) are integral membrane proteins that span the TGN membranes and recognize lysosomal enzymes that have been modified with mannose 6-phosphate. These receptors then localize the enzymes to the lysosomes.

What Is Responsible for Recognizing Lysosomal Enzymes and Localizing Them