Type II collagen gene mutations alter the properties of cartilage tissue and are known to cause _______.
A)osteogenesis imperfecta
B)Ehler-Danlos syndromes
C)Alport syndrome
D)dwarfism and skeletal deformities
E)diabetes

Question

Quizplus · Accepted Answer

Type II collagen is a major component of cartilage tissue. Mutations in the type II collagen gene can alter the properties of the cartilage tissue and lead to dwarfism and skeletal deformities. Osteogenesis imperfecta is caused by mutations in the genes responsible for collagen production in bones, while Ehler-Danlos syndromes are caused by mutations in genes that affect the production of collagen in the skin, joints, and blood vessels. Alport syndrome is caused by mutations in the genes responsible for type IV collagen production, which is found in basement membranes. Diabetes is not associated with type II collagen gene mutations.

Type II Collagen Gene Mutations Alter the Properties of Cartilage