Which of the following is typified by an epithelial-mesenchymal transition or EMT? (Select all correct choices)
A)formation of the mesoderm during gastrulation in a chick or mammalian embryo
B)cells breaking away from a cohesive epiblast
C)fusion of sperm and egg
D)formation of cartilage

Question

Quizplus · Accepted Answer

An epithelial-mesenchymal transition or EMT is a process in which epithelial cells lose their cell-cell adhesion and apical-basal polarity to acquire a mesenchymal, migratory phenotype. This process is involved in various physiological and pathological events, such as the formation of the mesoderm during gastrulation in a chick or mammalian embryo, and cells breaking away from a cohesive epiblast. Fusion of sperm and egg or formation of cartilage does not involve EMT.

Which of the Following Is Typified by an Epithelial-Mesenchymal Transition