Why Might Large Aggregates of Mitochondria Be Located in the Muscle

Why might large aggregates of mitochondria be located in the muscle cells of individuals with ragged red fiber disease?

A) the poorly functioning organelles proliferate in an attempt to meet cellular energy needs, just as they would for an athlete in training
B) the abnormal mitochondria are using all ATP they produce to replicate at an abnormally high rate
C) the mitochondria are excessively fragile and are damaged during biopsy, so that counting reveals an unrealistic assessment of their numbers
D) all choices are implausible