You modify the gene for an integral membrane protein so that the cytoplasmic portions of the protein are deleted. When the gene is inserted in cells, what happens to the mobility of this protein in the membrane?
A)It moves much greater distances than the intact protein.
B)It moves much smaller distances than the intact protein.
C)It does not move at all.
D)It is not inserted into the membrane so nothing can be learned about their mobility.
E)It flips to the opposite leaflet.

Question

Quizplus · Accepted Answer

Deleting the cytoplasmic portions of an integral membrane protein reduces the interaction of the protein with the cytoskeleton and other cytoplasmic components. This reduction in interactions allows the protein to move more freely within the membrane, leading to greater mobility compared to the intact protein.

You Modify the Gene for an Integral Membrane Protein So