A pharmacist is looking for a drug which will prevent an enzyme from working by binding to it as an inhibitor. Which of the inhibitors listed as choices will prove most effective, given equality in other considerations such as solubility, toxicity and stability?

Question

Quizplus · Accepted Answer

The lower the dissociation constant (K_d) of a substance, the stronger its binding affinity to an enzyme. Therefore, Substance P with a dissociation constant of 0.001 will prove to be the most effective inhibitor as it has the strongest binding affinity to the enzyme.

A Pharmacist Is Looking for a Drug Which Will Prevent