The main buffer system operating to maintain stable blood pH is made up of:

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The main buffer system operating to maintain stable blood pH is the carbonic acid/bicarbonate ions system. This system works by accepting or donating hydrogen ions to maintain the pH balance. Carbonic acid can release or accept a hydrogen ion to become bicarbonate or vice versa, depending on the pH of the blood. This process helps to regulate the blood pH within a narrow and stable range.

The Main Buffer System Operating to Maintain Stable Blood PH