On pulmonary function testing, which of the following lung abnormalities are common in patients with severe cystic fibrosis?
I. Obstructive pattern
II. Restrictive pattern
III. Airway hyperreactivity
IV. Normal pattern when asymptomatic

Question

Quizplus · Accepted Answer

Pulmonary function testing initially demonstrates air flow obstruction. As the disease progresses, both a restrictive and an obstructive pattern can be seen, along with a decrease in air flow. About 50% of patients with CF have a positive methacholine challenge test, which indicates airway hyperreactivity.

On Pulmonary Function Testing, Which of the Following Lung Abnormalities