A Patient with a Cough Has a Suspicious Lung Lesion

A patient with a cough has a suspicious lung lesion, a mediastinal lymph mass, and several bone lesions. What test is indicated to determine histology and staging of this cancer?

A) Biopsy of a bone lesion
B) Bone marrow aspiration and biopsy
C) Bronchoscopy with lung biopsy
D) Thoracentesis and pleural fluid cytology