If HIV first enters the cell in an endocytotic vesicle, instead of directly fusing with the plasma membrane, then
A) HIV infection should be hindered by microtubule polymerization inhibitors such as nocodazole.
B) HIV infection should be more efficient at lower temperatures.
C) intact cortical actin microfilaments should interfere with HIV infection.
D) cells lacking integrins should be resistant to HIV infection.
E) addition of ligands for other cell-surface receptors to stimulate their endocytosis should increase the efficiency of HIV infection.

Question

Quizplus · Accepted Answer

Microtubule polymerization inhibitors like nocodazole would hinder the transport of endocytotic vesicles within the cell, thereby hindering HIV infection if it relies on endocytosis.

If HIV First Enters the Cell in an Endocytotic Vesicle