According to the induced fit hypothesis of enzyme catalysis, which of the following is correct?
A) The binding of the substrate depends on the shape of the active site.
B) Some enzymes change their structure when activators bind to the enzyme.
C) A competitive inhibitor can outcompete the substrate for the active site.
D) The binding of the substrate changes the shape of the enzyme's active site.
E) The active site creates a microenvironment ideal for the reaction.

Question

Quizplus · Accepted Answer

The induced fit hypothesis states that the enzyme's active site is not a perfect fit for the substrate initially. Instead, the active site changes its shape and creates a better fit for the substrate upon its binding. Therefore, the binding of the substrate changes the shape of the enzyme's active site.

According to the Induced Fit Hypothesis of Enzyme Catalysis, Which