Which of the following statements describes enzyme cooperativity?
A) A multienzyme complex contains all the enzymes of a metabolic pathway.
B) A product of a pathway serves as a competitive inhibitor of an early enzyme in the pathway.
C) A substrate molecule bound to an active site of one subunit promotes substrate binding to the active site of other subunits.
D) Several substrate molecules can be catalyzed by the same enzyme.
E) A substrate binds to an active site and inhibits cooperation between enzymes in a pathway.

Question

Quizplus · Accepted Answer

Enzyme cooperativity occurs when the binding of a substrate molecule to one active site of a multi-subunit enzyme complex enhances the affinity of the other active sites for substrate molecules. This positive feedback mechanism increases the efficiency of enzyme catalysis and allows for rapid and coordinated regulation of metabolic pathways. Choice B describes feedback inhibition, choice D describes enzyme promiscuity, and choice E describes non-cooperative inhibition. Choice A is not necessarily related to enzyme cooperativity.

Which of the Following Statements Describes Enzyme Cooperativity