Phosphofructokinase is an important control enzyme in the regulation of cellular respiration. Which of the following statements correctly describes phosphofructokinase activity?
A) It is inhibited by AMP.
B) It is activated by ATP.
C) It is activated by citrate, an intermediate of the citric acid cycle.
D) It catalyzes the conversion of fructose 1,6-bisphosphate to fructose 6-phosphate, an early step of glycolysis.
E) It is an allosteric enzyme.

Question

Quizplus · Accepted Answer

Phosphofructokinase is an allosteric enzyme that plays a key role in regulating glycolysis. It is inhibited by ATP and activated by AMP, not the other way around. It catalyzes the conversion of fructose 6-phosphate to fructose 1,6-bisphosphate, not the reverse.

Phosphofructokinase Is an Important Control Enzyme in the Regulation of Cellular