In eukaryotes, general transcription factors
A) are required for the expression of specific protein-encoding genes.
B) bind to other proteins or to a sequence element within the promoter called the TATA box.
C) inhibit RNA polymerase binding to the promoter and begin transcribing.
D) usually lead to a high level of transcription even without additional specific transcription factors.
E) bind to sequences just after the start site of transcription.

Question

Quizplus · Accepted Answer

General transcription factors bind to other proteins or to a sequence element within the promoter called the TATA box. This binding helps to recruit RNA polymerase and initiate transcription.

Note: Option A is incorrect because general transcription factors are necessary for the expression of all protein-encoding genes, not just specific ones. Option C and option D are incorrect because general transcription factors do not inhibit RNA polymerase binding or lead to high levels of transcription without additional specific transcription factors. Option E is incorrect because general transcription factors bind to sequences within the promoter, not just after the start site of transcription.

In Eukaryotes, General Transcription Factors