BRCA1 and BRCA2 are considered to be tumor-suppressor genes because
A) they prevent infection by retroviruses that cause cancer.
B) their normal products participate in repair of DNA damage.
C) the mutant forms of either one of these promote breast cancer.
D) the normal genes make estrogen receptors.
E) they block penetration of breast cells by chemical carcinogens.

Question

Quizplus · Accepted Answer

BRCA1 and BRCA2 are involved in repairing DNA damage, and mutations in these genes can lead to the accumulation of genetic mutations that can promote cancer. Therefore, their wild-type products are considered tumor suppressors.

BRCA1 and BRCA2 Are Considered to Be Tumor-Suppressor Genes Because