For mapping studies of genomes, most of which were far along before 2000, the three-stage method was often used. Which of the following is the usual order in which the stages were performed, assuming some overlap of the three?
A) genetic map, sequencing of fragments, physical map
B) linkage map, physical map, sequencing of fragments
C) sequencing of entire genome, physical map, genetic map
D) cytogenetic linkage, sequencing, physical map
E) physical map, linkage map, sequencing

Question

Quizplus · Accepted Answer

The usual order for the three-stage method in mapping studies of genomes is to first create a linkage map, then a physical map, and finally sequence the fragments. This allows for a systematic approach to understanding the structure and organization of genes and their positions on chromosomes. The other choices listed do not follow this standard order.

For Mapping Studies of Genomes, Most of Which Were Far