Use the following information to answer the following questions.
In those parts of equatorial Africa where the malaria parasite is most common, the sickle-cell allele constitutes 20% of the β hemoglobin alleles in the human gene pool.
-If the sickle-cell allele is recessive, what proportion of the population should be susceptible to sickle-cell anemia under typical conditions?
A) 0.04
B) 0.16
C) 0.20
D) 0.32
E) 0.80

Question

Quizplus · Accepted Answer

Given that the sickle-cell allele (s) frequency is 0.20, the normal allele (S) frequency would be 0.80. Since sickle-cell anemia occurs in individuals with two sickle-cell alleles (ss), the proportion of the population with sickle-cell anemia is (0.20)^2 = 0.04.

Use the Following Information to Answer the Following Questions