Which of the following cells are involved in cell-mediated immunity and also respond to class I MHC molecule-antigen complexes?
A) cytotoxic T cells
B) natural killer cells
C) helper T cells
D) macrophages
E) B cells

Question

Quizplus · Accepted Answer

Cytotoxic T cells are involved in cell-mediated immunity and respond to class I MHC molecule-antigen complexes. Natural killer cells do not require MHC molecules for activation and do not have antigen-specific receptors. Helper T cells respond to class II MHC molecule-antigen complexes. Macrophages are antigen-presenting cells that display both class I and class II MHC molecules and activate both cytotoxic T cells and helper T cells. B cells are involved in humoral immunity and do not directly recognize MHC molecules.

Which of the Following Cells Are Involved in Cell-Mediated Immunity