According to the European Journal of Clinical Pharmacology, the half-life of the ACE inhibitor lisinopril increases from 12 hours in people with normal kidney function to 24 hours in people with mild kidney failure. A group of patients takes a 5-mg dose of lisinopril at 6 am. The rate that lisinopril decreases in the bloodstream is given by
for normal kidney function and
for impaired kidney function.
After 16 hours, what is the difference of the amount of lisinopril in the bloodstream between a person with normal kidney function and a person with impaired kidney function?
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