In nucleophilic substitution reactions, the nucleophile must have a greater affinity for the electropositive species than the original substituent.

Question

Quizplus · Accepted Answer

This is true because nucleophilic substitution reactions involve the nucleophile replacing the original substituent on the electrophilic species. For this to occur, the nucleophile must have a greater attraction to the electrophilic species than the original substituent.

In Nucleophilic Substitution Reactions, the Nucleophile Must Have a Greater