Identify the True Statement About Bicarbonate Ions (HCO₃⁻)

Identify the true statement about bicarbonate ions (HCO₃⁻) .

A) Normal plasma HCO₃⁻ concentration is 23-27 mEq/liter in systemic arterial blood.
B) Their concentration increases as carbon dioxide is exhaled.
C) Their concentration increases as blood flows through systemic capillaries.
D) No HCO₃⁻ is found in the intracellular fluid.
E) Their exchange with Cl^- helps maintain the correct balance of cations in the intracellular fluid and the extracellular fluid.