Phosphodiesterases (PDE's) are naturally produced enzymes that degrade cAMP inside of the cytosol of cells. Some pharmaceuticals are PDE inhibitors. How would these drugs affect your sense of smell?

Question

Quizplus · Accepted Answer

PDE inhibitors prevent the degradation of cAMP by blocking the action of phosphodiesterases. This leads to an increase in cAMP levels within the cell. In the context of olfactory cells, higher cAMP levels enhance the signal transduction process that leads to the perception of smell, thereby strengthening the sense of smell.

Phosphodiesterases (PDE's) Are Naturally Produced Enzymes That Degrade CAMP Inside