Serotonin reuptake inhibitors are commonly used as antidepressants and function exactly as their name implies: they inhibit the reuptake of serotonin from the synaptic cleft by the pre-synaptic neuron. What effect will this have on these serotonin pathways?

Question

Quizplus · Accepted Answer

Serotonin reuptake inhibitors prevent the reuptake of serotonin by the presynaptic neuron, which means that more serotonin will remain in the synaptic cleft and be available to bind to receptors on the postsynaptic neuron, thereby increasing the effects of serotonin on the postsynaptic neuron.

Serotonin Reuptake Inhibitors Are Commonly Used as Antidepressants and Function