Aldosterone Is a Steroid Hormone That Regulates the Balance of Ions

Aldosterone is a steroid hormone that regulates the balance of ions in the body by increasing transcription and insertion of Na⁺ channels in kidney epithelial cells. Which statements are correct about the signal transduction pathway aldosterone initiates in kidney epithelium?

A) aldosterone binds to plasma membrane receptors
B) occupied aldosterone receptors directly bind to DNA
C) second messengers activate protein kinases and phosphorylation
D) relay molecules pass the signal from receptor to the nucleus