Binding of nerve growth factor to a receptor tyrosine kinase causes all of the following except
A) dimerization of the receptor
B) hydrolysis of GTP on a G protein
C) cross-phosphorylation of the receptor
D) interaction of the receptor with the relay proteins

Question

Quizplus · Accepted Answer

Binding of nerve growth factor to a receptor tyrosine kinase triggers dimerization of the receptor, cross-phosphorylation of the receptor, and interaction of the receptor with relay proteins. However, it does not cause hydrolysis of GTP on a G protein as receptor tyrosine kinases are not coupled to G proteins. This process is more characteristic of G protein-coupled receptors.

Binding of Nerve Growth Factor to a Receptor Tyrosine Kinase