Which of the following is a difference between receptor tyrosine kinases and G protein coupled receptors?
A) Dimerization of the receptor is necessary for tyrosine kinase receptors but not G protein coupled receptors.
B) Receptor tyrosine kinases are the main type of receptors for interleukins, while G protein coupled receptors are the main type of receptors for steroids.
C) Tyrosine kinase domains are located extracellularly, while G protein coupled receptors are located intracellularly.
D) Receptor tyrosine kinases produce the second messenger cAMP, while G protein coupled receptors do not.

Question

Quizplus · Accepted Answer

Receptor tyrosine kinases require dimerization of the receptor for activation, while G protein coupled receptors do not. This dimerization allows for the cross-phosphorylation of tyrosine residues and activation of downstream signaling pathways. G protein coupled receptors, on the other hand, activate signaling pathways through the activation of intracellular G proteins, rather than through tyrosine phosphorylation.

Which of the Following Is a Difference Between Receptor Tyrosine