Cholera toxin works by permanently locking G_s protein in the on position in infected cells. What effect will it have on the signal transduction pathway? A) it will increase intracellular cAMP levels B) it will inhibit cAMP phosphodiesterase C) it will lead to deactivation of protein kinase A D) it will prevent adenylyl cyclase producing more cAMP

Question

Quizplus · Accepted Answer

Cholera toxin permanently activates the G protein GS, which in turn leads to constitutive activation of adenylyl cyclase and continuously elevated levels of cAMP.

Cholera Toxin Works by Permanently Locking Gs Protein in the on Position

Cholera Toxin Works by Permanently Locking G_s Protein in the on Position