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Pertussis Toxin, Also Known as Whooping Cough Toxin, Inhibits the Alpha

Question 104

Multiple Choice

Pertussis toxin, also known as whooping cough toxin, inhibits the alpha subunit of Gi from being activated. What might be a cellular mechanism of this toxin's action?


A) It enhances the dissociation of G alpha and G beta/gamma subunits.
B) It irreversibly activates G alpha subunit in GTP bound state.
C) It prevents association between the G alpha subunit and the receptor.
D) It stimulates the binding of G alpha subunit to adenylyl cyclase.

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