A/An ________ occurs when the number of cases of a particular disease during a particular time is significantly higher than it might be otherwise.

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An epidemic refers to a sudden increase in the number of cases of a disease beyond what is normally expected in a specific population or geographical area. It is often localized to a particular region and can be contained with proper measures. Pandemic, on the other hand, refers to a global outbreak of a disease affecting large populations across multiple continents or countries. Epidemiology is the study of the distribution and determinants of health and disease in populations. A distribution issue refers to a problem in the supply chain or logistical management of a product, which is not relevant in the context of this question.

A/An ________ Occurs When the Number of Cases of a Particular