The excessive and chronic production of cortisol by the adrenal cortex or by the administration of glucocorticoids in large doses for a period of several weeks or longer can cause _____.

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Excessive and chronic production of cortisol or the administration of glucocorticoids in large doses for a long period can cause Cushing's syndrome, which is characterized by weight gain, moon face, excessive hair growth, high blood pressure, and other symptoms. Hyperthyroidism is caused by excessive production of thyroid hormone, diabetes mellitus is caused by insulin resistance, and Addisonian crisis is caused by adrenal insufficiency. None of these conditions are specifically caused by excessive cortisol production.

The Excessive and Chronic Production of Cortisol by the Adrenal