What recessive disorder results in non-normal shaped blood cells that clog up blood vessels and cause pain, increased susceptibility to disease and early death?

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Sickle-cell anaemia is a recessive genetic disorder where the shape of the red blood cells is abnormal, which leads to the formation of a sickle shape. These abnormal-shaped cells can clog up blood vessels, leading to pain, increased susceptibility to disease, and early death. Tay-Sachs is a genetic disorder that affects the nervous system, mainly in infants, causing developmental delays, blindness, and death. Trisomy-21 is also known as Down syndrome and results from an extra copy of chromosome 21. Malaria is not a genetic disorder but rather a disease caused by a parasitic infection transmitted by mosquitoes.

What Recessive Disorder Results in Non-Normal Shaped Blood Cells That