Which environmental stressor appears to be a significant factor in the later development of neurocognitive disorder, including Alzheimer's disease?

Question

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Repeated head trauma, such as sports-related concussions or multiple instances of physical abuse, has been shown to increase the risk of developing neurocognitive disorders later in life, including Alzheimer's disease. Smoking, poverty, and exposure to high levels of aluminum have all been suggested as possible environmental factors, but their direct links to the development of these conditions are not yet fully understood.

Which Environmental Stressor Appears to Be a Significant Factor in the Later