Which of the following immunoglobulins has the highest molecular weight?
A) IgA
B) IgD
C) IgE
D) IgM

Question

Quizplus · Accepted Answer

IgM has the highest molecular weight among all the immunoglobulins. This is because IgM is a pentamer, which means it is made up of five individual immunoglobulin units. Each of these units is a Y-shaped molecule consisting of four polypeptide chains, resulting in a total molecular weight of around 900 kDa. In contrast, the other immunoglobulins (IgA, IgD, IgE, and IgG) are monomers or dimers and have lower molecular weights.

Which of the Following Immunoglobulins Has the Highest Molecular Weight