What happens to T cells that fail to recognize and interact with MHCs during maturation?
A) They are left to circulate in the blood.
B) They are converted to other types of cells.
C) They are eliminated through a selection process.
D) They are stored in the liver as reserves.

Question

Quizplus · Accepted Answer

T cells undergo a selection process during maturation in the thymus. Those that fail to recognize and interact with MHC molecules undergo negative selection and are eliminated to prevent self-reactive T cells from causing autoimmune diseases. Therefore, the correct answer is option C – they are eliminated through the selection process.

What Happens to T Cells That Fail to Recognize and Interact