How many high-energy phosphate bonds are cleaved during the activation of the β-oxidation of fatty acids?

Question

Quizplus · Accepted Answer

Two high-energy phosphate bonds are cleaved during the activation of the β-oxidation of fatty acids. Specifically, the first step involves the conversion of a fatty acid to fatty acyl-CoA, which requires the input of one ATP molecule to form fatty acyl-AMP and pyrophosphate. The fatty acyl group is then transferred to CoA, releasing AMP and reforming ATP. Overall, this process cleaves two high-energy phosphate bonds.

How Many High-Energy Phosphate Bonds Are Cleaved During the Activation