Only the S-enantiomer of naproxen inhibits the COX-1 and COX-2 enzymes, the R-enantiomer is a strong liver toxin. Therefore, only enantiomerically pure naproxen is sold in US pharmacies. Unfortunately, the classic synthesis leads to a racemic mixture. Which base do you use to separate the two enantiomers by recrystallization?

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The Answer of Only the S-enantiomer of naproxen inhibits the COX-1 and COX-2 enzymes, the R-enantiomer is a strong liver toxin. Therefore, only enantiomerically pure naproxen is sold in US pharmacies. Unfortunately, the classic synthesis leads to a racemic mixture. Which base do you use to separate the two enantiomers by recrystallization?

Only the S-Enantiomer of Naproxen Inhibits the COX-1 and COX-2