Rank the following substituents in order of increasing priority.

Question

Quizplus · Accepted Answer

The prioritization of substituents is determined by the Cahn-Ingold-Prelog (CIP) rules. The CIP rules assign priority based on the atomic number of the atoms directly attached to the stereocenter, with higher atomic number receiving higher priority. In this case, the substituent with the highest atomic number at the stereocenter is the one containing a bromine atom (IV), followed by the one containing a chlorine atom (I), then the one containing a methyl group (II), and finally the one containing a hydrogen atom (III). Therefore, the correct order of increasing priority is III, I, II, IV, which corresponds to choice C.

Rank the Following Substituents in Order of Increasing Priority