In the figure below, which depicts the activation step in bacterial DNA replication, the letter Q points to ________, and the letters R and S point to ________, respectively.
A) DnaA-ATP proteins; 9-mer repeats within oriC and 13-mer sequences
B) Primase; oriC and 13-mer repeats
C) SeqA protein; 13-mer repeats and 9-mer basepairs within oriC
D) DamA methylase; 9-mer repeats within oriC and 13-mer repeats
E) gyrase; 13-mer repeats and 9-mer sequences within oriC

Question

In the figure below, which depicts the activation step in bacterial DNA replication, the letter Q points to ________, and the letters R and S point to ________, respectively. 
A) DnaA-ATP proteins; 9-mer repeats within oriC and 13-mer sequences 
B) Primase; oriC and 13-mer repeats 
C) SeqA protein; 13-mer repeats and 9-mer basepairs within oriC 
D) DamA methylase; 9-mer repeats within oriC and 13-mer repeats 
E) gyrase; 13-mer repeats and 9-mer sequences within oriC

Quizplus · Accepted Answer

Q points to the DnaA-ATP proteins, which are responsible for initiating DNA replication by binding to and unwinding 9-mer repeats within the oriC region of the bacterial chromosome. R and S point to specific sequences within the oriC region, namely 9-mer and 13-mer repeats, respectively, which are recognized by the DnaA protein to initiate replication. Primase, SeqA, DamA methylase, and gyrase are not directly involved in the activation step of bacterial DNA replication.

In the Figure Below, Which Depicts the Activation Step in Bacterial