Which of the following statements is true concerning the use of cyclic di-GMP as a second messenger?
A) It activates the expression of flagellin genes and thus enhances motility.
B) It is found in all microbes: bacteria, archaea, and eukaryotic microbes.
C) The action of diguanylate cyclase produces it.
D) It decreases in level as biofilm is produced.
E) Phosphodiesterase can convert GMP to cyclic di-GMP.

Question

Quizplus · Accepted Answer

Cyclic di-GMP is produced from GTP by the action of diguanylate cyclase. It serves as a second messenger in a variety of microbial processes, including biofilm formation, regulation of motility, and virulence. The other answer choices are not true statements regarding cyclic di-GMP. For example, A is incorrect because cyclic di-GMP typically reduces motility and is associated with biofilm formation. B is incorrect because cyclic di-GMP is primarily found in bacteria and some archaea, but not eukaryotes. D is incorrect because cyclic di-GMP typically increases in level as biofilm is produced. E is incorrect because phosphodiesterase can convert cyclic di-GMP to GMP, not the other way around.

Which of the Following Statements Is True Concerning the Use