When studying an enzymatic reaction, should one consider $$\Delta$$G, $$\Delta$$G?, or $$\Delta$$G?' when considering the thermodynamics of the reaction, and why?

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Quizplus · Accepted Answer

$$\Delta$$G⁰ is the standard free energy change, which assumes the reaction is taking place under standard conditions with all reactants and products at 1M concentration. This is not always the case in biological systems, where the concentrations of substrates and products can vary widely, making $$\Delta$$G⁰ less useful. $$\Delta$$G⁰' is similar to $$\Delta$$G⁰, but it also takes into account the pH and ionic strength of the reaction, which can be more relevant in biological systems. However, it still assumes standard concentrations of substrates and products, so it is not the best choice for studying enzymatic reactions. $$\Delta$$G considers the concentrations of substrates and products under defined conditions, such as a specific pH, making it a good choice for studying enzymatic reactions. $$\Delta$$G⁰ takes into account standard conditions as well as biochemically relevant conditions such as the concentrations of substrates and products and is therefore the best choice.

When Studying an Enzymatic Reaction, Should One Consider Δ\DeltaΔ G Δ\DeltaΔ G?, Or

When Studying an Enzymatic Reaction, Should One Consider $\Delta$ G $\Delta$ G?, Or