Which first lady boldly challenged some of her husband's policies during his presidency?

Name: Which first lady boldly challenged some of her husband's policies during his presidency?
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Question

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Eleanor Roosevelt was known for being outspoken and advocating for various social justice issues during her husband Franklin D. Roosevelt's presidency. She was especially known for advocating for civil rights and challenging segregation, as well as pushing for greater involvement of women in politics.

Which First Lady Boldly Challenged Some of Her Husband's Policies