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X-Linked Hyper IgM Syndrome (XHIM) Is an Immunodeficiency Disorder Caused

Question 61

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X-linked hyper IgM syndrome (XHIM) is an immunodeficiency disorder caused by mutations of the gene encoding CD154. Why is this disease characterized by recurrent infections (starting in childhood) and elevated serum levels of IgM?

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B-cell activation requires two sets of s...

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