Mycobacterium, Trypanosomia, and Leishmania spp. are all unique in that once they are intracellular, they down-regulate the IFN-gamma receptor, causing
A) immune-response suppression.
B) opsonization.
C) complement activation.
D) superantigen reactions.
E) high fever responses.

Question

Quizplus · Accepted Answer

These pathogens down-regulate the IFN-gamma receptor, which is critical for activating immune cells such as macrophages to clear infected cells, leading to immune-response suppression.

Mycobacterium, Trypanosomia, and Leishmania Spp