The Major Challenge with Treating Flesh-Eating Disease Caused by Streptococcus

The major challenge with treating flesh-eating disease caused by Streptococcus pyogenes is that

A) the bacterium is a multidrug-resistant pathogen.
B) no antibiotic is useful, because it's a mixed infection.
C) toxin-encoding phage also encode antibiotic-degrading enzymes.
D) the causative agent is an MRSA.
E) rapid necrosis of infected tissue limits treatment access.