The action of which of the following enzymes both activates glycogen breakdown and inhibits glycogen synthesis?
A) protein kinase A
B) protein kinase C
C) phosphorylase kinase
D) protein phosphatase 1
E) None of the answers is correct.

Question

Quizplus · Accepted Answer

Protein kinase A (PKA) is activated in response to elevated levels of cyclic AMP (cAMP) and leads to the activation of glycogen breakdown by phosphorylating and activating phosphorylase kinase, which in turn activates glycogen phosphorylase. PKA also inhibits glycogen synthesis by phosphorylating and inhibiting glycogen synthase.

The Action of Which of the Following Enzymes Both Activates