Why is the T state of glycogen phosphorylase less active?
A) The adjacent amino acids are not phosphorylated, and thus the catalysis cannot be carried out.
B) The active site is partially blocked.
C) ATP cannot be bound by the T state.
D) Glucose-1-phosphate remains bound to the active site.
E) None of the answers is correct.

Question

Quizplus · Accepted Answer

The T state (tense state) of glycogen phosphorylase is less active because the active site is partially blocked, preventing the efficient binding of substrate and thus reducing the enzyme's catalytic activity.

Why Is the T State of Glycogen Phosphorylase Less Active