Which of the following is toxic due to its ability to react with neighboring sulfhydryls of dihydrolipoyl groups, thus blocking their reoxidation to lipoamide?
A) fluoroacetate
B) carbon monoxide
C) arsenite
D) rotenone
E) cyanide

Question

Quizplus · Accepted Answer

Arsenite is toxic because it can react with neighboring sulfhydryls of dihydrolipoyl groups, which are essential for the function of the pyruvate dehydrogenase complex and alpha-ketoglutarate dehydrogenase complex, thus blocking their reoxidation to lipoamide and disrupting cellular respiration.

Which of the Following Is Toxic Due to Its Ability