What are the steps involved (in order) in the conversion of pyruvate to acetyl-CoA?
A) decarboxylation, oxidation, transfer to CoA
B) decarboxylation, transfer to CoA, oxidation
C) oxidation, decarboxylation, transfer to CoA
D) oxidation, transfer to CoA, decarboxylation
E) None of the answers is correct.

Question

Quizplus · Accepted Answer

The conversion of pyruvate to acetyl-CoA involves three main steps in the following order: decarboxylation (removal of a carbon as CO2), oxidation (transfer of electrons to NAD+ to form NADH), and finally, the transfer of the resulting acetyl group to Coenzyme A (CoA), forming acetyl-CoA.

What Are the Steps Involved (In Order) in the Conversion